Emerging threat · Drug-resistant fungus

Candida auris 2026

United States · Drug-resistant yeast · CDC & state health departments
Sources: CDC Candida auris Tracking and state health departments.

About Candida auris

Cause
Candida auris, a drug-resistant yeast (a fungus), recently reclassified as Candidozyma auris but still widely called C. auris
How it spreads
Person to person in hospitals and nursing homes, via hands, surfaces and equipment; it survives weeks on surfaces
Community or food risk?
No. It does not spread in daily life, through the air, or through food
Treatment
Echinocandin antifungals first; some strains resist all drugs. No vaccine

Why health officials are worried
Candida auris breaks the usual rules for a fungus. It passes from patient to patient inside healthcare facilities, lingers on bed rails and equipment for weeks, and shrugs off the antifungal drugs meant to treat it. The CDC ranks it an urgent antimicrobial-resistance threat, its highest tier. The good news for most people is that it is not a community threat: it targets the already seriously ill, not the healthy public.

Sources: CDC C. auris Tracking · CDC Infection Control

Treatments & Vaccines in Development

Candida auris is treated with antifungal drugs, but resistance is the whole problem: the first-line class still works against many strains, a growing share resist everything available, and there is no vaccine. Here is what care looks like.

EchinocandinsTreatment
First-line
Standard of care

Most Candida auris infections are treated first with an antifungal class called echinocandins (micafungin, caspofungin or anidulafungin), which still work against many strains. Treatment should be guided by an infectious-disease specialist and by lab tests showing which drugs the specific strain responds to.

CDC C. auris Treatment
Newer antifungals when resistantTreatment
For resistant strains
Multiple

When a strain resists echinocandins, or resists all three main antifungal classes, options run short. Doctors may turn to drug combinations or newer antifungals such as rezafungin, and others like ibrexafungerp and fosmanogepix are being studied. A small but growing number of strains are resistant to everything currently available, which is the core worry.

CDC Antifungal Resistance
VaccineVaccine
None available

There is no vaccine against Candida auris. Because it spreads inside healthcare facilities and clings to surfaces, the main defense is infection control: screening patients who may carry it, isolating those who do, strict hand hygiene, and cleaning with disinfectants proven to kill it.

CDC C. auris Infection Control
Approved / in usePositive trial resultsIn clinical trialsEarly researchHalted